High throughput device for rapid cellular metabolic characterization
Solicitation number 25-58185
Publication date
Closing date and time 2025/11/25 14:00 EST
Last amendment date
Description
Description:
OBJECTIVE:
The cell culture scale-up team (CCSU) has a requirement for an instrument for rapid cellular metabolic characterization. The instrument will be used to characterize and screen the phenotype and the metabolic requirements of cell lines developed at the NRC and used in large-scale bioreactors.
BACKGROUND:
Cell lines can be used to produce monoclonal antibodies, recombinant proteins, viral vectors, vaccines, viruses and virus-like-particles. In large-scale bioreactor, the metabolic profile of a cell line has a critical impact on its productivity. The presence of certain nutrients in the cell culture media is also a strong determinant of the cell line performance. Therefore, we are looking for an instrument that will enable measurements of multiple metabolites in parallel at 32oC to 37oC in live cells. We are particularly interested in measurements of metabolites involved in mitochondrial activity and respiration. We also need to screen different compounds that might improve cell growth and productivity in a high-throughput fashion.
All the deliverables must be received within 2 months after the contract award date.
Contract duration
The estimated contract period will be 2 month(s).
Trade agreements
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Canadian Free Trade Agreement (CFTA)
Reason for limited tendering
A contracting officer can use limited tendering for specific reasons outlined in the applicable trade agreements. The reason for this contract is described below:
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None
Contact information
Contracting organization
- Organization
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National Research Council of Canada (NRC)
- Address
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1200 Montreal Road
Ottawa, Ontario, K1A 0R6Canada
- Contracting authority
- Veronica Exari
- Phone
- (343) 576-3252
- Email
- Veronica.Exari@nrc-cnrc.gc.ca
- Address
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6100 Royalmount Road
Montreal, Quebec, H4P 2R2Canada
Bidding details
Related notices
Contracts awarded (1) This tender notice has 1 related award notices. Click to collapse
This is a list of other contracts that were awarded related to solicitation number 25-58185. Click the link under “More details” to view the contract details.
Company name
|
Contract number
|
Amendment date
|
Award date
|
More details |
|---|---|---|---|---|
| Biolog Inc. | 1038710 | 2026/03/30 | 2026/01/22 | Viewthe details of contract 1038710 for Biolog Inc. |