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COMPUTATIONAL CHEMISTRY SIMULATIONS OF PHARMACEUTICAL BASED AGENTS

Solicitation number W7702-206207/A

Publication date

Closing date and time 2020/01/08 16:00 EST

Last amendment date


    Description
    Trade Agreement: Canadian Free Trade Agreement (CFTA)
    Tendering Procedures: The bidder must supply Canadian goods and/or services
    Competitive Procurement Strategy: Best Overall  Proposal
    Comprehensive Land Claim Agreement: No
    Nature of Requirements: 
    
    
    
    IMPORTANT: This tender is part of Public Works and Government Services Canada’s initiative to submit bid submission files electronically using epost Connect. Interested bidders should refer to Part 2 of the solicitation document entitled Instructions to bidders/offerors/suppliers, as the case may be, for instructions on how to participate and submit their files electronically for this tender.
    
    ** WE HAVE MOVED! Effective September 30, bids will be received at Canada Place, Suite 1000, 9700 Jasper Avenue, Edmonton AB, T5J 4C3**
    
    
    1.  TITLE: COMPUTATIONAL CHEMISTRY SIMULATIONS OF PHARMACEUTICAL BASED AGENTS, DRUG DISCOVERY AND CHEMICAL ABSORPTION
    
    2.  SECURITY:
    There is no security requirement associated with the requirement.
    
    3.  REQUIREMENT:
    Defence Research and Development Canada (DRDC)-Suffield Research Centre requires information on the physical properties of some pharmaceutical based agents (PBAs) and medical countermeasures (MCMs) that they cannot determine experimentally. They also require information on how these molecules interact with various solutions and biological systems.  Current calculations in the literature do not account for enough of the physical environment surrounding the PBAs or MCMs to produce accurate representations of the interaction of these molecules in biological systems. DRDC-Suffield would like high-level quantum calculations to predict these interactions. For drug-repurposing DRDC-Suffield Research Centre also requires high-level calculations of hybrid quantum mechanics/molecular mechanics (QM/MM) to discover drugs against protein targets based on approved drugs by US Federal Drug Administration (FDA). For small molecule capture using Metal-Organic Frameworks (MOFs), the screening calculations are needed to determine the best candidates of MOFs for chemical absorption.
    
    
    To qualify a bid will have to consist of no less than 80% of goods and/or services of Canadian origin. 
    
    
    4. EVALUATION AND SELECTION:  
    Mandatory and point rated technical evaluation criteria are included in Annex "D" of the solicitation. 
    
    The responsive bid with the highest number of points will be recommended for award of a contract, provided that the total evaluated price does not exceed the budget available for this requirement.
    
    5. OWNERSHIP OF INTELLECTUAL PROPERTY:
    Any intellectual property arising from the performance of the Work under the Contract will vest in Canada. 
    
    6. PERIOD OF CONTRACT: 
    It is anticipated that any contract will be effective from date of Contact award to 2020-03-31 with three (3) option years and two (2) "GO-NO GO" optional tasks (Tasks 5.2.3 and 5.2.4).
    
    
    Contracting Authority
    
    Lorraine Jenkinson  
    Procurement Specialist 
    Public Works and Government Services Canada 
    Procurement Branch, Western Region 
    Canada Place, Suite 1000
    9700 Jasper Avenue NW
    Edmonton AB, T5J 4C3 
    
    Telephone: 587-337-2458  
    Facsimile: 780-497-3510 
    E-mail address: lorraine.jenkinson@pwgsc-tpsgc.gc.ca
    
    Delivery Date: Above-mentioned
    
    The Crown retains the right to negotiate with suppliers on any procurement.
    
    Documents may be submitted in either official language of Canada.

    Contract duration

    Refer to the description above for full details.

    Trade agreements

    • Canadian Free Trade Agreement (CFTA)

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    Contact information

    Contracting organization

    Organization
    Public Works and Government Services Canada
    Address
    11 Laurier St, Phase III, Place du Portage
    Gatineau, Quebec, K1A 0S5
    Canada
    Contracting authority
    Jenkinson, Lorraine
    Phone
    (587) 337-2458 ( )
    Email
    lorraine.jenkinson@pwgsc-tpsgc.gc.ca
    Fax
    (780) 497-3510
    Address
    Canada Place/Place du Canada
    10th Floor/10e étage
    9700 Jasper Ave/9700 ave Jasper
    Edmonton, Alberta, T5J 4C3

    Buying organization(s)

    Organization
    Department of National Defence
    Address
    101 Colonel By Dr
    Ottawa, Ontario, K1A0K2
    Canada
    Bidding details

    Full details regarding this tender opportunity are available in the documents below. Click on the document name to download the file. Contact the contracting officer if you have any questions regarding these documents.

    Tender documents
    Document title Amendment no. Language Unique downloads Date added
    001
    English
    6
    001
    French
    1
    000
    English
    22
    000
    French
    2

    Access the Getting started page for details on how to bid, and more.

    Eligibility and terms and conditions

    Government of Canada tender and awards notices, solicitation documents, and other attachments are fully accessible and available free of charge and without having to register on CanadaBuys.

    Information may be available on another source prior to being available on CanadaBuys. You may have received this information through a third-party distributor. The Government of Canada is not responsible for any tender notices and/or related documents and attachments not accessed directly from CanadaBuys.canada.ca.

    Government of Canada tender or award notices carry an OpenGovernment License - Canada that governs its use. Related solicitation documents and/or tender attachments are copyright protected. Please refer to our terms and conditions page for more information.

    Summary information

    Notice type
    Request for Proposal
    Language(s)
    English, French
    Region(s) of delivery
    Alberta
    Procurement method
    Competitive – Selective Tendering
    Selection criteria
    Highest Combined Rating of Technical Merit and Price

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