Amphasys AG

Impedance Flow Cytometer for cell characterization

Switzerland based Amphasys is a leading supplier of cell analysis instruments based on Impedance Flow Cytometry as a working principle. The advantages of this method are: label-free, no marker or dyes needed, no incubation time, immediate results, applicable for all human and animal cells, yeast, algae, bacteria, fungi. Due to the fact that no optical detection is used, even turbid and autofluorescent solutions can be analyzed. The instrument is compatible for inline or online measurements because the cells are not altered. This also allows the combination with cell sorting for later use in regenerative medicine or tissue culture. The technology allows real-time measurements for e.g., process control in bioreactors, and provides information about viability and cell count as well as the metabolic status of the cells. To control fermentation processes for example, this enables to be aware at any time of the process in which phase the cells are. The technology is also used for pollen analysis. It allows systematic screening of lines and routine quality control of pollen quality for improved breeding and seed production. Amphasys’ technology is the only method to get fast, easy and accurate information of pollen viability and the content of aberrant cells. The instrument is available in a portable form to perform measurements directly in the field for crops with short-lived pollen like wheat, corn and rice.