Nuclear Magnetic Resonance (NMR) Spectrometer System

Trade Agreement: WTO-AGP/NAFTA/AIT/Canada FTAs with
Peru/Colombia/Panama
Tendering Procedures: All interested suppliers may submit a bid
Attachment: None
Competitive Procurement Strategy: Best Overall  Proposal
Comprehensive Land Claim Agreement: No
Nature of Requirements: 
Nuclear Magnetic Resonance (NMR) Spectrometer System

H4134-133091/A
Alan Takasaki
Supply Specialist
Public Works and Government Services Canada
Acquisitions Branch Vancouver,
2nd floor,  800 Burrard St
Vancouver, BC  V6Z 0B9
Telephone: 	(604)775-7605    	Facsimile: 	(604)775-7526
E-mail address: al.takasaki@pwgsc.gc.ca

The PWGSC Vancouver office provides procurement services to the
public in English.

This year, Vancouver Drug Analysis Service (DAS) laboratory is
forecast to receive and analyze over 28,000 drug exhibits from
seizures by police services, the RCMP and border services from
Manitoba, Saskatchewan, Alberta, British Columbia and the
Territories.  Of these, an estimated 350 samples will be further
analyzed quantitatively, to precisely identify the percent
composition of a commodity.  This number is severely restricted
because of current technical limitations; Vancouver DAS offers
quantitation services for cocaine, heroin, methamphetamine and
MDMA only.  Using existing methodology, the turnaround times for
six samples of one drug type range between two to three days,
and the analyses require certified standards, which are costly,
time-consuming to obtain.  Frequently the lab is requested to
provide a purity determination on a new emerging drug which it
cannot do with these limitations.

A Nuclear Magnetic Resonance (NMR) spectrometer is being sought
to improve and expedite quantitation, among other important
applications.  Quantitative NMR (qNMR) is a robust method
recognized for the certification of reference materials. 
Because NMR is insensitive to impurities, the ratios obtained
are highly precise; there is no need for chemically identical
standards, or calibration, or conditioning, and turnaround time
can be less than two minutes per sample.  This application of
NMR is well established; the American Drug Enforcement
Administration (DEA) has developed a turn-key, automated
analysis system for its field labs to quantitate hundreds of
commodities and have been using qNMR for almost two decades. 
The DEA Special Testing Laboratory has agreed to provide
Vancouver DAS with a copy of the macroinstructions that they
have developed in-house for the automated analysis of samples
for quantitation and facilitate sharing of methods and
conclusions from analyses of interest (ie. international
trafficking investigations) as shipping forensic drug samples
cross international borders is not practical, especially on a
time sensitive scenario.  These macros are written using the
Agilent coding language MAGICAL II. 
Requirement:
DAS of Health Canada require the supply, delivery installation
and commissioning of  ONE(1) only, 400 MHz Nuclear Magnetic
Resonance (NMR) Spectrometer  that comprised of a
superconducting magnet, magnet stand, high-sensitivity probe, a
console, an autosampler and a fully customizable, automated
acquisition and processing software that is compatible with the
macros written by the DEA, or comes with equivalent macros that
are ready to use and automated.

Sample Request
Bidders interested in bidding should request the test sample for
quantitation analysis as soon as possible so that the result can
be included in the bidder's bid response. Due to international
legislation, the test sample can only be mailed to a Canadian
address. This sample will include a mixture of pseudoephedrine
and caffeine; procurement of solvent and internal standard, D2O
and maleic acid, required in the analysis will be the bidder's
responsibility.

Bidders are to send an email to the al.takasaki@pwgsc.gc.ca and 
Elizabeth.perez@pwgsc.gc.ca . The subject Line should read "Test
Sample Request - RFP H3134-133091/A".  In your email, please
provide the complete Canadian mailing address, name, telephone #
and email address.

Delivery date for all hardware and software:	On or before March
28, 2014
Completion date of all installation and commissioning: On or
before April 30, 2014 
Completion of all training:  On or about May 15, 2014.
Delivery Date: Above-mentioned

The Crown retains the right to negotiate with suppliers on any
procurement.

Documents may be submitted in either official language of Canada.