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Mass Spectrometer

Solicitation number 6D063-132702/A

Publication date

Closing date and time 2014/01/10 15:00 EST

    Trade Agreement: WTO-AGP/NAFTA/AIT/Canada FTAs with
    Tendering Procedures: Generally only one firm has been invited
    to bid
    Attachment: None
    Non-Competitive Procurement Strategy: Exclusive Rights
    Comprehensive Land Claim Agreement: No
    Vendor Name and Address: 
    AB Sciex LP
    71 Four Valley Dr
    Concord Ontario
    Nature of Requirements: 
    Marlene Hall
    Supply Specialist
    Telephone:  204 984-6423
    File No.: 6D063-132702/A
    TITLE:	Mass Spectrometer
    Public Works and Government Services Canada (PWGSC), on behalf
    of Public Health Agency Canada (PHAC), Canadian Science Centre
    for Human and Animal Health (CSCHAH), intends to negotiate with
    AB Sciex LP for the provision of a QTRAP 6500 Mass Spectrometer.
    Public Health Agency Canada (PHAC) has a requirement for a QTRAP
    6500 Mass Spectrometer for biological research. The Mass
    Spectrometry and Proteomics (MSP) Core Facility supports
    National Microbiology Laboratory (NML) in mass spsectrometry
    analysis. The MSP provides NML with access to mass spectrometry
    and proteomics instrumentation, software, methods, training,
    information, and networking. MSP's key technologies include
    2D-LV/MS/MS and MALDITOF MS, which are used to measure
    biological systems at the protein level. These tools are used to
    provide services and applications for better prevention,
    treatment and diagnosis of infectious disease. The QTRAP 6500
    and accompanying components will be for providing NML with new
    diagnostic services,  e.g., target quantitiaiton for biomarker
    verification, validation, and detection. These new services are
    needed to help fulfill NML mandate for rapid, molecular-based
    diagnostics of infectious disease and bioterrorism-telated
    Any interested supplier must demonstrate by way of a statement
    of capabilities that its product meets the following mandatory
    Due to space constraints, require a bench-top triple quadrupole
    mass spectrometry system that has a footprint no larger than 32
    inches by 32 inches (not including a nitrogen generator or
    computer). The instrument's top panel must be able to support
    the weight of typical HPLC and nanoLC devices, and the LC must
    be of the appropriate size (same or smaller footprint and less
    than 32-inches in height) and spill-proof design.
    The MS and LC systems must be able to switch between nano-flow
    (100-1000 nl/min) and micro-flow (1-50 ul/min) easily
    (plug-and-play) and fast (within minutes). This is required to
    enable switching between different applications for our various
    clients at NML that require more sensitivity (nano-flow) or more
    robustness (micro-flow).
    As a core lab servicing many clients with many different types
    of biological samples, we require simple plug-and-play nano-LC
    chips/cartridges for rapid (< 1 min) changing of columns and
    easy-of-use.  This is also required to enable out-sourcing of
    the column costs to our clients. NanoLC column cartridges must
    be separate from the electrospray tip to enable changing of the
    tip independently of the column.  The columns must be housed in
    a temperature controlled chamber for minimizing variability
    within analytical separations. 
    A 5-2000 m/z mass range for quadrupole scanning is required for
    analysing target peptides of interest.
    MRM-triggered full scan MS/MS carried out simultaneously for
    peptides detected by MRM in a cycle time less than 5 ms which
    required for structural validation of target peptides without
    compromising quantitative (MRM) measurements. MS/MS collected
    simultaneously, within the same run to the MRM experiment, must
    have product ion sensitivities to detect and sequence 1-5 amol
    of BSA peptides on a nanoLC column.
    Must have the ability to carry out MRM3, an experiment for the
    quantitation of peptides when background interferences in
    complex matrices prevent the required LLOQ to be attained by MRM
    alone.  Instrument must support this experiment by both hardware
    and software and provide automated tuning for MRM3 methods for
    peptides.   MRM3 experiments must be performed in a cycle time
    less than 200 ms for analytical reproducibility for nanoLC
    separations of peptides in biological proteolytic digests.
    Ion detector capable of up to 6 orders or more of linear dynamic
    range required for spanning the concentration range of target
    peptides of interest.
    AB Sciex LP is the only known supplier that can provide a Mass
    Spectrometer that meets all of the mandatory performance
    The following limited tendering reasons pertain to this
    Government Contract Regulations, Part 1, Section 6(d) only one
    person is capable of performing the contract.
    Government on Internal Trade (AIT), Article 506-12(b) where
    there is an absence of competition for technical reasons and the
    goods or services can be supplied only by a particular supplier
    and no alternative or substitute exists;
    North American Free Trade Agreement (NAFTA), 1016.2(b) where,
    for works of art, or for reasons connected with the protection
    of patents, copyrights or other exclusive rights, or proprietary
    information or where there is an absence of competition for
    technical reasons, the goods or services can be supplied only by
    a particular supplier and no reasonable alternative or
    substitute exists;
    World Trade Organization Agreement on Government Procurement
    (WTO-AGP), Article XV(b) when, for works of art or for reasons
    connected with protection of exclusive rights, such as patents
    or copyrights, or in the absence of competition for technical
    reasons, the products or services can be supplied only by a
    particular supplier and no reasonable alternative or substitute
    The equipment must be delivered on or before March 31, 2014, FOB
    AB Sciex LP
    71 Four Valley Drive
    Concord, On
    L4K 4V8
    Delivery Date: Above-mentioned
    You are hereby notified that the government intends to negotiate
    with one firm only as identified above. Should you have any
    questions concerning this requirement, contact the contracting
    officer identified above.
    An Advance Contract Award Notice (ACAN) allows departments and
    agencies to post a notice, for no less than fifteen (15)
    calendar days, indicating to the supplier community that it
    intends to award a good, service or construction contract to a
    pre-identified contractor. If no other supplier submits, on or
    before the closing date, a Statement of Capabilities that meets
    the requirements set out in the ACAN, the contracting authority
    may then proceed with the award.  However, should a Statement of
    Capabilities be found to meet the requirements set out in the
    ACAN, then the contracting authority will proceed to a full
    tendering process.
    Suppliers who consider themselves fully qualified and available
    to provide the services/goods described herein, may submit a
    statement of capabilities in writing to the contact person
    identified in this Notice on or before the closing date of this
    Notice. The statement of capabilities must clearly demonstrate
    how the supplier meets the advertised requirements.
    The PWGSC file number, the contracting officer's name and the
    closing date of the ACAN must appear on the outside of the
    envelope in block letters or, in the case of a facsimile
    transmission, on the covering page.
    The Crown retains the right to negotiate with suppliers on any
    Documents may be submitted in either official language of Canada.

    Contract duration

    Refer to the description above for full details.

    Trade agreements

    • World Trade Organization Agreement on Government Procurement (WTO GPA)
    • Canada-Panama Free Trade Agreement
    • Agreement on Internal Trade (AIT)
    • Canada-Colombia Free Trade Agreement
    • Canada-Peru Free Trade Agreement (CPFTA)
    • North American Free Trade Agreement (NAFTA)

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    Contact information

    Contracting organization

    Public Works and Government Services Canada
    11 Laurier St, Phase III, Place du Portage
    Gatineau, Quebec, K1A 0S5
    Contracting authority
    Hall, Marlene
    (204) 984-6423 ( )
    (204) 983-7796
    PO Box 1408, Room 100
    167 Lombard Ave.
    Winnipeg, Manitoba, R3C 2Z1

    Buying organization(s)

    Public Health Agency of Canada
    130 Colonnade Road
    Ottawa, Ontario, K1A 0K9
    Bidding details

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    Summary information

    Notice type
    Advance Contract Award Notice
    English, French
    Region(s) of delivery

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