High-Throughput Surface Plasmon Resonance (SPR) Platform

Suppliers can find the complete tender document(s), at no cost, on: https://uwo.bonfirehub.ca.

Procuring Entity:
University of Western Ontario (Western)
Procurement Services
1151 Richmond Street
London, Ontario, Canada, N6A 3K7

Contact:
Scott Roth sroth6@uwo.ca         

Procurement Method:
Open tender whereby all interested Suppliers may submit a Proposal.

Description:
The RFP is an invitation to submit offers for Supply and Install High-Throughput Surface Plasmon Resonance (SPR) Platform for Screening and Characterization in the Drug Discovery Process.
Biotherapeutics, typified by therapeutic antibodies (mAbs), have demonstrated exceptional efficacies on many diseases. Moreover, the therapeutic response of biotherapeutics can be also greatly enhanced by small molecular enzyme inhibitors.
Our goal is to obtain a high-throughput SPR instrument capable of automating workflows related to the discovery of therapeutic antibodies and small molecular inhibitors, and the screening and characterization of antibody-antigen interactions, enzyme-inhibitor interactions and protein-protein interactions.
The proposed instrumentation will be integrated into the multi-user Western Biotherapeutics Centre in the Department of Biochemistry at Western.  This brand new research core will enable us to discover and develop first-in-class therapeutic mAbs, biologics and inhibitors.
The affinities and kinetics of protein-protein, protein-DNA/RNA, and protein-small molecule interactions need to be measured in real-time with high precision and accuracy. All experiments will have the ability to be performed with small amounts of samples, in an automated and high throughput manner. Acquisition of such an SPR system will accelerate the antibody and drug discovery process, allowing thousands of drug candidates, ligands and interactions to be quantified and characterized via capture-based kinetics and affinity screens. Please download the RFP documents for further details.
Estimated Quantities:
Available within the tender document

Submission Details:
All tender submissions must be uploaded electronically at https://uwo.bonfirehub.ca

Submission Deadline:
June 12, 2024 at 12:00 PM ET

Public Opening:
Not Applicable

Conditions for Participation:
Available within the tender document(s)

Mandatory Submission Requirements:
 

1. Appendix B- Submission Form
2. Appendix C- Rate Bid Form
3. Appendix D- Reference Form
4. Appendix E- Deliverables and Technical Requirements Questionnaire
5. Appendix F- Proponents Checklist

Complete submission requirements are provided within the tender document(s).


Scored Submission Requirements:
 

1. Mandatory Requirements
2. Experience, Qualifications and References
3. Technical Requirements
4. Service and Support
5. Sustainability
6. Value- Added Ideas
7. Accessibility (AODA)
8. Pricing
9. In-kind

This procurement is covered by Chapter 5 of the Canadian Free Trade Agreement (CFTA).
This procurement is covered by Chapter 19 of the Canada-European Union Comprehensive Economic Trade Agreement (CETA).

Delivery Date:
Summer 2024

Duration of Agreement:
Upon receipt of equipment and satisfaction of obligations as set out in the Agreement.

Additional Options:
Available in the tender document(s)

Negotiation:
At the end of the evaluation process, Western may identify one or more Suppliers with whom it wishes to enter into negotiations, by written notification.  See tender document(s) for further detail.

Prequalification:
Not Applicable

Responses must be submitted in English.

Suppliers should note that information contained within this Tender Notice is subject to change.  Suppliers are encouraged to download the tender document(s) which contain the most current information.
 
If there is a conflict between the tender document(s) and this Tender Notice, the tender document(s) will take precedence.
 

Bidding and Documents are available on http://www.merx.com. Fees may apply; See https://www.merx.com/public/pricing for more information.